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Both of the two insulin-positive tumors were identified in 120-min post-injection scan of [ 18 F]FB(ePEG12)12-exendin-4 PET/CT, and one of the two was also detected in 30-min post-injection scan of [ 18 F]FB(ePEG12)12-exendin-4 and [ 68 Ga]DOTATOC PET/CT (Fig

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As the majority of patients with type 2 diabetes are overweight or obese this offers a potential advantage over older, established therapies, and DPP-4 inhibitors are being used in clinical practice as second-line therapy in addition to metformin in overweight and obese patients who fail to reach glycemic targets with metformin monotherapy