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However, another study reported that a group of T2DM patients treated with metformin plus liraglutide or metformin plus Ex-4 for 1 year experience an increase in resting energy expenditure compared to placebo treated controls when energy expenditure was adjusted for fat free mass (Beiroa et al., 2014)

Cycle Planning A reasonable annual structure: Run 12 weeks on (300500mcg/day) 6 weeks off 12 weeks on 8 weeks off

doi: 10.1016/j.tibs.2010.08.003 22 CamilliA.TilneyL

This quick-reference table helps set patient expectations: nausea is common but often transient, and titration and supportive care usually shorten the course

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