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It is noteworthy that the majority of these gastrointestinal manifestations are of a mild nature and predominantly occur during the titration phase (108)

As the number of new drugs increases, physicians must choose the right obesity treatment for each patient, individualising the balance of benefits and adverse effects, say the authors of a linked Editorial To view or add a comment, sign in What if the biggest challenge with Ozempic and similar drugs isn't losing weight

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Many patients reduce to half their peak dose once they reach stable weight

rather, it is a complex structural and inflammatory issue driven by underlying joint hypermobility, aberrant mast cell degranulation, and relentless systemic cytokine storms