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The human GST multi-gene superfamily is encoding for various ubiquitous cytosolic or soluble, mitochondrial and microsomal as well as peroxisomal homo- and heterodimeric transferases ( S -conjugation generates a less or non-toxic product with improved water solubility, favoring the exportation out of the cell and thereby contributing to DNA damage prevention and protection of the cellular integrity (Wang et al., 2001

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Youm, Y.-H

As a consequence, IGF-1 is synthesized and secreted at suboptimal levels