In the multiple-dose trial, eligible subjects were healthy males, aged 1864 years, with a BMI of 20.029.9 kg/m 2 , and males with T2D diagnosed within the last 10 years, treated with diet and exercise and/or metformin, aged 1864 years, with a BMI of 20.037.0 kg/m 2 and glycosylated haemoglobin (HbA 1c ) of 6.59.0%
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It will be important to continue monitoring side effect tolerability of the medication in the long term
Different support reps handled each exchange, and at least one email response did not address the question we asked, requiring a follow-up that added another 2472 hours to the resolution
Nonetheless, given the reduced FOXA1 expression induced by Ex-4 in our study, it is unlikely that the observed Ex-4-induced TG content reduction is due to the stimulation of peroxisomal fatty acid -oxidation
