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With conventional techniques for the microencapsulation of active pharmaceutical ingredients, the microspheres form when the solvent containing an active agent and a polymer is emulsified or dispersed in an immiscible solution by stirring, agitating, vibrating, or some other dynamic mixing technique, often for a relatively long period of time

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243 The TAMs are immune cells that exhibit immunosuppressive functions, and reducing TAMs infiltration can inhibit tumor growth and improve survival rate