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To handle stomach side effects, try different diets and adjust when you take your medicine

[10] Current evidence suggests that the risk of vision problems with GLP-1 medications appears primarily related to rapid glycaemic improvement in patients with pre-existing retinopathy rather than a direct medication effect across all patients

Animal studies used oral doses ranging from 5mg/kg to 50mg/kg to produce measurable effects on hippocampal synaptogenesis

doi: 10.1089/ars.2022.0191 13 OlsonKRStraubKD

However, the direct vascular protective effects of GLP-1 RAs, including anti-inflammatory and endothelial actions, could theoretically operate independently of baseline metabolic status [31]