Although vitamin C has an overall low toxicity risk in healthy individuals, consuming too much of it can cause some adverse gastrointestinal side effects, including cramps, nausea, and diarrhea (11, Additionally, since a high vitamin C intake increases the bodys absorption of non-heme iron, consuming too much vitamin C could cause problems for people with hemochromatosis, a condition in which the body retains too much iron ( Because of the potential side effects of excessive vitamin C, the IOM has established the following Tolerable Upper Intake Levels (UL) for the vitamin (11): summary To avoid gastrointestinal side effects, keep your vitamin C intake within the ULs established by the IOM
Purcell, A
A multicenter retrospective longitudinal study
We note that, for cases in which a recommendation by the HOP Panel appears to result in or allow a violation of the 2 times rule, we generally accept the HOP Panel's recommendation because those recommendations are based on explicit consideration of resource use, clinical homogeneity, site of service, and the quality of the claims data used to determine the APC payment rates
It taps into the bodys fat supply by supporting the transport of fatty acids to the muscles mitochondria where they can be burned off as energy