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Degradation or autophagy of ferritin in response to other regulators such as autophagy-associated protein (Atg) and Nuclear receptor coactivator 4 can result in release of Fe2+ from ferritin into the LIP [52]

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in 2023, they showed that SLC25A39 is not only a transporter but a dynamic sensor that regulates the amount of glutathione in the mitochondria and adjusts those levels accordingly