is it normal to have diarrhea on glp 1 GLP-1 Medication Side Effects: What's & What's Not GLP-1 Diarrhea: Mechanisms, Management &

Novo Nordisk already has an oral version of semaglutide, the active ingredient in Ozempic and Wegovy, on the market in Rybelsus, which was first approved in 2019, but that is indicated for treating Type 2 diabetes, not obesity

Pretreatment with each examined GLP-1 analogs, including GLP-1(736), liraglutide, and exendin-4, led to significantly reduced Ca 2+ responses (by 53.8%, 58.1%, and 72.2%, respectively)

Early studies suggest overlapping gastrointestinal issues, but longer follow-up is important because the drug also has glucagon receptor activity

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What Did the Study Find