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Future studies should also explore the potential of emerging therapies, such as dual and triple agonists (e.g., tirzepatide and retatrutide), which have shown even greater efficacy in weight loss [20, 21]

How Semaglutide (Ozempic/Wegovy) Regulates Hunger Signals and Satiety Semaglutide (the active ingredient in Ozempic and Wegovy) is a GLP-1 receptor agonist

The active ingredient in most weight loss drugs including Mounjaro, Wegovy and Ozempic mimics a hormone called glucagon-like peptide-1 (GLP-1)

Funding Open access funding provided by Universitat Rovira i Virgili

Combining retatrutide with anabolic substances or performance-enhancing drugs as sometimes discussed in online forums is not clinically sanctioned and may carry serious cardiovascular and endocrine risks