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Although research on KPV is less extensive in this domain, its capacity to attenuate expression of chemokines and inflammatory mediators in immune cells suggests it may act synergistically with other peptides to suppress gene signatures linked to sustained inflammatory activation (30)

Cartilage or synovial membrane samples were embedded in paraffin, and 5 m sagittal sections were obtained using a Polycut E microtome

The Nrf2/HO-1/GPX4 antioxidant signaling pathway may be an important intervention target for preventing drug-induced AKI containing AAI

Next, we performed mitochondrial morphology analysis of WT INS-1 832/3 cells treated with Control versus SPHKAP RNAi prior to vehicle or exendin-4 exposure (Fig

doi: 10.1172/jci.insight.59125