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According to WebMD, The more common B12 injection side effects are: Swelling at the injection site Mild dirhhea Itching Swelling in the body Low potassium (weakness, irregular heartbeat) There is a case report of an anaphylactic reaction to a B12 injection in a 55 year old women receiving cyanocobalamin, but these reactions are thought to be rare

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Total corrinoid, cobalamin (vitamin B12), and cobalamin analogue levels may be normal in serum despite cobalamin in liver depletion in patients with alcoholism

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It may be considered: During periods of high stress or fatigue During recovery from illness or surgery When clinical history suggests deficiency risk As part of a broader, supportive infusion plan All decisions are guided by clinical assessment , not symptom trends