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A reduction in hydrochloric acid and/or digestive enzyme insufficiency, common in the ageing population could contribute to low levels

I would not call this microdosing, either

doi: 10.3389/fneur.2021.729399

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In the United States it is not FDA-approved: it had been placed in the FDA's restricted 503A bulk-compounding category and was removed from that restricted list in April 2026 as part of a procedural review reset, with a federal advisory committee due to reassess it in mid-2026