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The exact causes of IR has not been fully determined, 36,37,38 but ongoing research seeks to better understand how IR develops

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The causes of restless leg syndrome are unknown, though science has uncovered some pertinent information and risk factors for developing RLS

Exenatide formulations show variable nausea rates: the twice-daily immediate-release preparation (Byetta) tends to produce higher rates of nausea (approximately 3050%), whilst the once-weekly extended-release formulation (Bydureon) demonstrates improved tolerability with nausea rates of approximately 1424%, according to their respective SmPCs