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The reduced payoff makes even the most crave-inducing unhealthy foods less desirable, and as a direct result, makes a person less likely to want to indulge in foods that would contribute to weight gain
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As such, centrally, but not peripherally, administered nesfatin-1 reproducibly causes reductions in food intake in rodents 231,232
Weight change from index to 1 year was descriptively assessed
Thought I was going to have to re-write the whole damned post
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