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But of course, GLP was another one early identified as well

FIGURE 17 5 Conclusion The expression of GLP-1R in tissues other than the pancreas, such as the brain, endocrine tissues, heart muscle, kidneys, lungs, muscle, and vascular tissues, as well as the proximal digestive and gastrointestinal tract, indicates that GLP-1 has a multifaceted regulatory role beyond glucose homeostasis mediated by insulin release

Canada GLP-1 Receptor Agonist Market Analysis The GLP-1 receptor agonist market in Canada was valued at USD 4.35 billion in 2025, supported by increasing prevalence of obesity and type 2 diabetes, expanding access to innovative diabetes therapies, and growing emphasis on chronic disease management

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This triple-action mechanism distinguishes it from existing approved agents such as semaglutide (GLP-1 only) or tirzepatide (GLP-1/GIP dual agonist)