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What GLP-1 Medications Actually Do to Your Body GLP-1 (glucagon-like peptide-1) receptor agonists work by: Suppressing appetite and increasing feelings of fullness Slowing digestion so you feel satisfied longer Regulating blood sugar and insulin response Originally developed for type 2 diabetes, drugs like semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro) are now widely prescribed for weight loss and the WHO formally recognises them as valid obesity treatments

[6] Perley and Kipnis estimated the intestinal component accounts for 50%-70% of the total insulin secreted after an oral glucose load

Safety depends less on the molecule and more on who made the vial, how it was tested, and how it was handled

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In addition, the guidelines were the first time the AAP issued comprehensive recommendations for how pediatricians should approach obesity treatment