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The investigation has sparked debate among healthcare professionals, regulators, and patient safety advocatesnot simply about one drug, but about a broader question: What happens when public demand for a promising therapy outpaces the regulatory process designed to evaluate its safety and effectiveness

The addition of B12 is one reason compounding pharmacies are legally permitted to prepare these formulations even when the brand-name version is available, since a compound with a meaningfully different formulation falls outside the scope of the approved product

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Patients should not make changes to their antihypertensive medication independently, even if they feel their blood pressure has improved following weight loss

Kristin Kirkpatrick, MS, RD, is a registered dietitian with over 20 years of experience in integrative nutrition