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The administration of candesartan is sufficient to block the isolation stress (24h isolation in individual metabolic cages)-induced increased binding of AT 1 R to PVN and to reduce the HPA response to stress (157)( Table 4 )

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In this study, we recruited 25 female patients with first episode schizophrenia (FES) who were drug nave at baseline and received 4 weeks of olanzapine monotherapy

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