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A diferencia de los agonistas tradicionales, que activan mltiples vas simultneamente, estas molculas ms recientes favorecen una activacin ms selectiva, centrada en los efectos teraputicos deseados

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Blood 91:288294 Niihara Y, Miller ST, Kanter J et al (2018) Investigators of the phase 3 trial of l-glutamine in sickle cell disease a phase 3 trial of l-glutamine in sickle cell disease