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BDNF modulates synaptic plasticity through several mechanisms: 1) BDNF promotes dephosphorylation of KCC2 and downregulates KCC2 expression via the TrkB pathway (164)

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In this study, we thoroughly investigated ACSL4/GPX4 and FSP1-mediated ferroptosis in oxalate-induced AKI, highlighting that targeting ferroptosis in renal tubular epithelial cells may be a promising strategy for treating and preventing the progression of this oxalate-induced nephropathy

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