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DISCUSSION By combining previous models and making a few parameter changes, we have created a new model of glutathione metabolism that we have used to investigate sexual dimorphism in the glutathione pathway in the liver

To test this hypothesis, we constructed the gpoA Cys36Ala mutant, which demonstrated a higher susceptibility to H 2 O 2 in reference to the wt strain, a similar phenotype displayed by the gpoA mutant (Fig 3B, Fig S2)

Second, increased understanding of the gut-blood barrier and oral bioavailability limitations has driven consumers toward more direct delivery methods

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