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Another subject, male 70 years of age, developed severe cellulitis of the lower extremity requiring hospitalization 2 wks after the last dose of ARA 290 and suffered a fatal myocardial infarction

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The activation and proliferation of glial cells, in turn, are useful in order to release signaling factors and to trigger a robust immune reaction consisting of brain-resident as well as peripherally recruited inflammatory cells

Reconstitute full vial or transfer unused powder to new sterile vial immediately (difficult to do properly)