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However, the potential reduction in healthcare resource use across both classes suggests a combination of both SGLT2is and oral GLP-1 RAs may confer long-term cost savings compared to SGLT2is and standard of care alone [32, 33]

Citations Klausen MK et al, "Once-weekly semaglutide versus placebo in patients with alcohol use disorder and comorbid obesity: a randomised, double-blind, placebo-controlled trial." The Lancet, May 2, 2026

The majority of these follow-on patents were filed between 2021 and 2022, coinciding with the launches of Mounjaro and Zepbound (Figure 10)

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