It plays a role in: Appetite signaling Satiety (feeling full) Blood sugar response Metabolic communication When GLP signaling is supported, many people experience: More manageable hunger cues Fewer intense cravings Steadier energy Better portion awareness As a Holistic Functional Nutritionist, I focus on supporting the bodys natural systems, not overriding them
Clinical trials show that cumulative weight loss accelerates as doses increase over the following months
For example, a patient who struggles with constant hunger may benefit most from a GLP-1 therapy, while someone who eats primarily in response to stress or emotion may respond better to a medication that targets neurological reward pathways
The results: The results of the SURMOUNT-1 trial are as follows: [1] On the 5mg dose , participants lost an average of 15 to 16% of their starting body weight On the 10mg dose , participants lost an average of 19.5% to 21.4% of their starting body weight On the 15mg dose , participants lost an average of 20.9% to 22.5% of their starting body weight Participants taking the placebo lost an average of 3.1% of their starting body weight Other findings included: Up to 91% of participants lost at least 5% of their starting body weight, compared to 35% taking the placebo Up to 57% of participants taking the 10mg and 15mg doses achieved weight loss of at least 20% , compared to 3% taking the placebo The trial also found reductions in blood pressure and waist circumference, which are known risk factors for cardiovascular disease Many participants reported an improvement in physical function, emotional, social and psychological well-being and quality of life Side effects were generally mild and included nausea, vomiting, diarrhoea and constipation
Vitamin B12 can also be given as a subcutaenous injection
