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Description

GLP-1 faces toward TM5 to form cation-pi stacking and hydrogen bond with the rotated down side-chain of R299 ECL2 , while that of W306 5.36b and R310 5.40b switch out from the receptor core to accommodate the approaching of histidine

This work benefited from access to Research Resources Centre and UICentre at University of Illinois at Chicago and used the platforms of the Grenoble Instruct-ERIC center (ISBG