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GLP-1s are predicted to become the best-selling drug class of 2024 (inclusive of diabetes and obesity) 2 The late-stage obesity pipeline is dominated by big pharma, and 8 of the top 20 pharma companies have a clinical stage asset in development The obesity pipeline has almost tripled in size since June 2023, and there are up to 6 new U.S

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Abstract Aim To evaluate the efficacy and safety of onceweekly subcutaneous semaglutide, a glucagonlike peptide1 (GLP1) analogue, versus oncedaily sitagliptin as addon to metformin in patients with type 2 diabetes (T2D) in a multiregional clinical trial