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Once my team and I had rebuilt this (we were in a team of 6), we were tasked with looking at the interactions between excitatory and inhibitory neurons to understand the relationship between synapse size and strength and their communication with nearby dendrites

Cortex 20 , 22872303 (2010)

This NAD+ elevation activates sirtuins (particularly SIRT1), enhances mitochondrial function, and preserves methylation capacity by reducing S-adenosylmethionine (SAM) consumption

This is especially important for organs with high cell turnover like the skin, liver, and digestive system

For example, understanding how fatigue impacts neuromuscular control and affects muscle activation patterns can help identify individuals with compromised stability or alignment