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Combination therapy with ibrexafungerp (Formerly SCY-078), a first-in-class triterpenoid inhibitor of (13)--d-glucan synthesis, and isavuconazole for treatment of experimental invasive pulmonary aspergillosis

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Thus, ASD is characterized by an imbalance of the processes of mitochondrial fusion, fission, and mitophagy that leads to contamination of the brain with dysfunctional mitochondrial fragments, insufficient energy supply to the brain tissues, and as a result, impairments of memory and synaptic function [187] contributing to ASD pathogenesis