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Chondrocyte ferroptosis contribute to the progression of osteoarthritis

The GIP pathway is studied in the context of the postprandial metabolic response, insulin secretion and interactions with GLP-1 signalling

Conversely, in cancer, where autophagy is often upregulated to promote survival, inhibiting autophagy while simultaneously targeting the UPS could lead to the accumulation of toxic proteins and induce cell death

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BPC 157 may serve as a novel mediator of Roberts cytoprotection, involved in maintaining of GI mucosa integrity, with no toxic effect