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Inhibition of ROS by GSH or its analogs has been reported to block HIV replication, whereas increased intracellular GSH levels have been shown to enhance African swine fever virus replication 156,157 , indicating that the effect of GSH on viral replication varies according to the virus type

In a long-term randomized, double-blind, placebo-controlled study among sufferers of cerebrovascular accidents at high risk of depression, daily supplementation with 2 mg of folic acid, 25 mg of vitamin B6, and 500 g vitamin B 12 significantly lowered the risk of major depressive episodes during a seven-year follow-up period compared to placebo (111)

Researchers have discovered that vitamin C may help increase glutathione levels by attacking free radicals first, thereby sparing glutathione

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