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One of the most common polymorphisms, affecting 20 to 50% of certain populations, is an absence of the GSTM1 gene (GSTM1 null), which decreases detoxification ability among other possible outcomes

It does not predict your response to Ozempic or determine your dose

doi: 10.1073/pnas.0510033103

Note that in a larger set of 77 human coronaviruses, a serine (S) in P4 is very common (12), and in addition the sequence SI in the TXNRD1 site is isosteric to TV, the aligned residues in the nsp12/13 site, because transfer of a methyl group from threonine to valine would result in serine and isoleucine

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