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Unfortunately, studies on this topic have mainly focused on normalising serum B12 concentrations with oral supplementation and should be interpreted with caution since the specific goal of treatment in symptomatic B12 deficiency is alleviating symptoms, and NOT to normalize B12 concentrations in the blood

A.MohamedN

If you are using a semaglutide with B12 formulation , the BUD assigned should specifically account for the combined stability, not just the semaglutide component

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In a press release, Vertex reported statistically significant improvement in pain compared to placebo as well as a clinically meaningful reduction in pain from baseline in both the abdominoplasty and bunionectomy randomized controlled trials. But the small molecule pill didnt do better than a combination of acetaminophen and the opioid hydrocodone, a secondary endpoint, for patients who were prescribed it after a tummy tuck or bunion surgery