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The Benoist 2014 study used the HGF/MET dimerization antagonist Hinge to block Dihexas procognitive activity in scopolamine-impaired rats, with oral Dihexa (2 mg/kg/day) reversing the scopolamine-induced Morris water maze deficit when administered alone but losing effect when co-administered with Hinge [3]

Hemoglobin (Hb), transferrin (Tf), thyroid hormones (T3 and T4), IgG levels, and antioxidant indicators, such as total antioxidant capacity (TAC), superoxide dismutase (SOD), and glutathione (GSH), were enhanced, whereas malondialdehyde (MDA) levels were reduced

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Point and squeeze to apply a gentle stream along the gum line