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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management (Ozempic, Rybelsus) and chronic weight management (Wegovy) in adults, with Wegovy also approved for adolescents 12 years and older with obesity

So, here are the main differences and similarities between oral and injectable semaglutide to help keep them top-of-mind: They work the same

A recent decision from the Federal Circuit has seriously called into question whether it was proper for Novo Nordisk to list these patents in the Orange Book (discussed below in connection with Wegovy and Rybelsus.) Either way, the injection device patents most likely did not impact the negotiated entry date for the generics since they will all expire before the 343 and 462 patents

Nothing bad happens immediately

Our medical weight loss professionals provide expert guidance to help you determine whether tirzepatide or semaglutide is the right fit for your weight loss journey