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In the UK, NICE guidance (TA875) recommends semaglutide only within specialist weight management services for specific patient groups

The regulator added that it is reviewing eight other submissions for generic semaglutide from different companies, with additional regulatory decisions expected in the coming weeks and months [Source: canada.ca/en/health-canada/news/2026/04/canada-becomes-the-first-g7-country-to-approve-a-generic-version-of-semaglutide.html]

Both sequences contain an even number of cysteines (Supplementary Table S6)

Some early data hints at modest changes, but this is not firmly settled, and B12 depletion is far more strongly linked to other medications (such as metformin) than to semaglutide