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Using both in vitro (hemin-induced ferroptosis in cultured neurons) and in vivo (collagenase-induced intracerebral hemorrhage in mice) models, the researchers illustrated that NAC effectively prevented hemin-induced ferroptotic cell death in cultured neurons and, when administered post-injury in mice, significantly reduced neuronal loss while enhancing functional recovery

It has been demonstrated that Parkinson's disease-affected patients suffer from 100-200 SNpc neuronal damages per day [119]

Nanomedicine 6, 12571272

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