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10 , Frontiers in Nutrition 2021 , , L- , 2

therefore, mice with significantly greater weights (20% above the average weight of all enrolled mice) were excluded

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RNA-seq analysis revealed that DEGs between 0 mg/kg and 2 mg/kg anwuligan-treated mice were significantly enriched in several key pathways, including metabolic pathways, protein digestion and absorption, retinol metabolism, MAPK signaling pathway, PI3KAkt signaling pathway, Wnt signaling pathway, PPAR signaling pathway, BMP signaling pathway, and TGF-beta signaling pathway

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