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Following a year of treatment with Mounjaro (tirzepatide), weight loss is around 20% or more, and diabetes symptoms can also be effectively controlled

In a randomized controlled study, people with type 2 diabetes who already took metformin, a medication for blood sugar regulation, either added semaglutide or tirzepatide to their medication line-up

In KCs, SIRT1 deacetylates the NF-B p65 subunit, inhibiting its transcriptional activity and reducing the expression of pro-inflammatory cytokines such as TNF-, IL-1, and IL-6