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Think of the glucagon receptor as a third tier, says Sue DeCotiis, MD, a triple-board certified weight loss specialist and a clinical instructor at the NYU Grossman School of Medicine in New York City

While higher-income individuals may manage to afford GLP-1s OOP, lower-income individuals who are more likely to be affected by obesity will face significant access barriers

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Receptor agonists bind to receptors and trigger intracellular signaling pathways that modulate physiological functions

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