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JAK inhibition increases bone mass in steady-state conditions and ameliorates pathological bone loss by stimulating osteoblast function

Kohda K, Kakegawa W, Matsuda S, Nakagami R, Kakiya N, Yuzaki M

It is vital to understand the nuance here

Horn, DO, MPH, DABOM, MFOMA, medical director at the University of Texas Center for Obesity Medicine and Metabolic Performance and clinical assistant professor in the department of surgery at University of Texas McGovern Medical School in Houston, said the weight loss observed in ATTAIN-2 was lower than what was observed in ATTAIN-1, but added that adults with type 2 diabetes usually lose less weight with obesity pharmacotherapy than the nondiabetes population

Stephen Appezzato Key Takeaways Federal exclusion of weight-loss drugs forces Medicare GLP-1 utilization into other FDA-approved indications, even as 2024 Part D gross GLP-1 spending reached $27.5 billion across 21.8 million claims