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found that DHA triggered ferroptosis to eliminate the activation of HSC, which characterized by iron overload, GSH depletion, lipid ROS accumulation, and peroxidation, whereas Fer-1 and Lip-1 inhibited the DHA effect (93)

In the liver, co-treatment markedly improved steatosis, and restored normal hepatic morphology

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Neuromuscular diseases Amyotrophic lateral sclerosis (ALS) ALS is a degenerative disease caused by gain of function mutations associated with a dominant SOD1 phenotype, a gene encoding the cytosolic antioxidant enzyme Cu, Zn-superoxide dismutase

The spread of breast cancer cells generally consists of the metastasis process, which is found in several solid tumours (117)