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For all their remarkable effectiveness, the current GLP-1 drugs have some limitations

The Bottom Line The most accurate GLP-1 side effects timeline is not a straight line from "sick in week 1" to "fully adjusted by month 3." Digestive symptoms are common early and during dose escalation

In this respect, more research efforts are essential and needed to minimize the risk of pulmonary aspiration and minimize anesthesia risk during sedated medical procedures in patients on GLP-1 RAs

[3] "Off-label prescribing" is when a healthcare professional prescribes a licensed medication in a way that differs from its officially approved usage

Similarly, Zhang et al.'s research also indicated that genetically predisposed GLP-1Ras were correlated with decreased risks of AF, cardiac arrest, and ventricular fibrillation (124)