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Entre los pentadecapptidos sintticos derivados de secuencias parciales de protenas gstricas de origen natural, el BPC-157 ha suscitado un inters sostenido y variado en la investigacin preclnica por sus interacciones con mltiples sistemas de sealizacin

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Keywords: type 2 diabetes, obesity, insulin, glucagon, GLP-1, GLP-1R, incretin, metabolism Introduction Maintaining metabolic homeostasis is essential in all living organisms, as it provides energy in the form of adenosine trisphosphate (ATP) required for cellular processes to proceed

This drew our attention to the ubiquitin-related protein UBE2m, which is a ubiquitin-conjugating enzyme essential for the neddylation that was significantly enriched (Fig