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Results claimed the greater efficiency of EV-mediated treatment compared to the direct administration of the drugs, where TMZ-loaded EVs showed the best antiproliferative effects on both PDAC and GBM [16, 181]

Laboratory investigations commonly examine 5-Amino-1MQs interaction with nicotinamide N-methyltransferase (NNMT) , an enzyme involved in cellular methylation balance and metabolic signaling networks

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Patients should be encouraged to maintain adequate fluid intake in order to minimize this problem