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i.e., insulin resistance and metabolic syndrome Side effects include: Nausea Vomiting Diarrhea Constipation Stomach pain Acid reflux Heartburn Bloating Gastritis Muscle loss & bone density reduction Can also include: Headaches Fatigue Ozempic Face (sagging or aging skin) Mood changes/depression Injection site reactions More serious side effects include: Pancreatitis Kidney damage Vision changes Allergic reactions (swelling, rash, difficulty breathing) Hypoglycemia (low blood sugar) Thyroid cancer risk Comprehensive data on its safety and efficacy beyond 2 years is limited

Subsequently, the AAA+ module binds and hydrolyzes ATP to drive conformational changes in the protease and promote substrate unfolding

doi: 10.1186/S40001-025-02479-6 163

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If a dose is missed by more than 5 days, the patient should skip that dose and resume the regular schedule on the next scheduled day [4]