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SCFA, short-chain fatty acid

The dose-findings studies reported here not only documented the superior efficacy of GLP1/E in the management of metabolic alterations in our obese PCOS model, including lowering body weight and adiposity, as well as improvement of glucose handling and insulin resistance, but also highlighted a non-monotonic effect of this dual agonist in PNA mice, with optimal effects being achieved with submaximal doses

In human liver cells and rat urine, glucuronidation (particularly metabolite M19) is the main detoxification pathway

Its ability to neutralise free radicals and regulate oxidative stress makes it an essential component of overall health