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To corroborate the findings we observed significantly higher 4-HNE and S-Nitrotyrosine levels in the spermatozoa of infertile patients in comparison to their fertile counterparts

The functional expansion of Nrf2 in proliferating cells directs the enhancement of anabolic metabolism, maintains redox homeostasis and further promotes the activation of PI3KAkt signaling, suggesting the presence of positive feedback between Nrf2 and the PI3KAkt pathway in proliferating cells (Figure 9)

Free Radical Damage Free radicals are highly reactive, unstable molecules produced in the body as byproducts of normal metabolic processes

Suner, S

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