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Overall, baseline characteristics were well balanced, with a mean age of 60.1 years and 85.5% male participants

Distinct signalling bias arising through activation of the GLP-1R by different ligands (including OXM) has recently been established and may, at least in part, underlie differences in the physiological profile of naturally occurring ligands of the GLP-1R 12

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The weight loss was rapid, observed as early as Day 8, and persisted through the study duration